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br exclusively Rios de la Rosa et al b
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exclusively (Rios de la Rosa et al., 2017b). Cells were pelleted (1000 rpm, 5 min, 25 °C) and re-suspended in 400 µL PBS. The inter-nalization of DY547-NP was determined on 10,000 individual and live 4hydroxy Nonenal with the BD LSRFortessa cytometer (BD Bioscience, San Jose CA, USA) equipped with
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br The major strength of this study was the use
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The major strength of this study was the use of data from Swedish population-based registers with high completeness, minimizing selection and information bias. Through linkage be-tween different registers we were able to study the underlying causes of absence from work, taking several important fa
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br In addition to confirm that ER stress was regulated
2020-08-28
In addition to confirm that ER stress was regulated by ROS, the HC030031 were treated with the ROS scavenger NAC along with CBD. As shown in Fig. 4E, CBD remarkably increased ER stress-related proteins, and NAC partially reversed this effect of CBD, suggesting that ROS induced by CBD contributes t
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br SUMMARY br Sal like protein and
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36 SUMMARY 38 Sal-like protein 4 and Krüppel-like factor 5 expression is 39 strongly up-regulated in capping UNC-1999 protein of muscle Z- 40 line a subunit 1 (CAPZA1)-overexpressing cells after Heli- 41 cobacter pylori infection. High epithelial splicing regulatory 42 protein
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br Fig Standard mortality ratios by possible occupational ex
2020-08-28
Fig. 1. Standard mortality ratios by possible occupational exposure and no known occupational exposure. Table 5 Mesothelioma standardized mortality ratios by possible occupational exposure and gender. No occupational exposure Possible occupational exposureb SMR, Standard mortality rat
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br Varadhachary GR Abbruzzese JL Wolff RA Ahmad SA
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Varadhachary GR, Abbruzzese JL, Wolff RA, Ahmad SA, et al. Frequency and intensity of postoperative surveillance after curative treatment of pancreatic cancer: a cost-effectiveness analysis. Ann Surg Oncol 2013;20(7):2197e203. [32] Witkowski ER, Smith JK, Ragulin-Coyne E, Ng SC, Shah SA, Tseng
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br Cellular uptake studies br Rhodamine B loaded nanoparticl
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3.6. Cellular uptake studies Rhodamine-B loaded nanoparticles (R-SLN) were prepared by re-placing EGCG with Rhodamine B and conjugated with BBN (RB-SLN) for comparative cellular uptake studies (Xu et al., 2009). For quanti-tative studies, 1 × 105 cells per well were seeded in 12-well plates and
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br fluorescence signal distribution br Cell experiments
2020-08-18
fluorescence signal distribution. 2.7. Cell experiments In resistant cells, mutant p53 increase the tolerance to chemother-apeutic drug. Depleting mutant p53 would be an efficient way to de-crease drug resistance. In order to prove the ability of BPNs-PDA-PEG-PEITC to suppress the function o
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b iframe width height src https www youtube com embed
2020-08-18
r> 2.3. Culture of human primary pancreatic ductal epithelial LY-500307 and murine organoids 2.3.1. Human primary pancreatic cells epithelial cells (HPPE) Human primary pancreatic cells epithelial cells (HPPE) were pur-chased from Cell Biologics, Inc. (Chicago, IL) and grown in T25 tissue cul
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br To investigate whether the cell population of tumor
2020-08-18
To investigate whether the cell population of tumor-like co-spher-oids formed on CS-HA may be influenced by the ratio of MIA JSH 23 and PSCs seeded initially, the respective cell numbers and sizes of the formed spheroids were determined in the conditions of different cell ratios. As shown in Fig.
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br Research in context br Evidence before this study
2020-08-18
Research in context Evidence before this study Genetic mutations in key biomarkers are known to predict out-comes and response to treatment in metastatic colorectal cancer. Concordance in these biomarkers between the primary and meta-static sites is an important factor to consider with both
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R G Stirling S M Evans
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[24] R.G. Stirling, S.M. Evans, P. McLaughlin, M. Senthuren, J. Millar, J. Gooi, L. Irving, Contents lists available at ScienceDirect European Journal of Medicinal Chemistry Research paper Bimetallic titanocene-gold phosphane complexes inhibit invasion, metastasis, and angiogenesis-assoc
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br As shown in Fig all compounds tested significantly increa
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As shown in Fig. 4, all compounds tested significantly increased calcium levels. Taking into account that the ER acts as the major calcium store in EPZ031686 (Pereira et al., 2018, 2015a), we hypothesized that this organelle could be involved in the toxicity elicited by benzoquinones, reason f
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br We next determined whether BACH is functionally involved
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We next determined whether BACH1 is functionally involved in the increased glycolysis. Using the CRISPR-SAM approach, we (E) Schematic showing intratracheal administration of pSECC lentiviruses encoding Cre recombinase, CAS9, and the gRNAs sgTom or sgBach1. (F) Metastasis incidence in KP mic
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br The interpretation and generalizability of our findings a
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The interpretation and generalizability of our findings are limited by their cross-sectional nature and by the sample, which consists of outpatient participants in a psychosocial intervention study at a large regional cancer centre. The prevalence of demoralization was some-what higher in the stud