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br Considering the significant impact of AAMP on
2020-07-29
Considering the significant impact of AAMP on ERK1/2 activation and the interaction between AAMP and EGFR, we wondered if EGFR is an intermediate protein in AAMP-ERK1/2 regulation. We measured A siCTRL siAAMP-1 siAAMP-2 -Icotinib PI +Icotinib AnnexinV-FITC B C siCT
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br Acknowledgments The National Cancer Database
2020-07-29
Acknowledgments: The National Cancer Database (NCDB) is a joint project of the Commission on Cancer of the American College of Surgeons and the American Cancer Society. The Commission on Cancer’s NCDB and the hospitals participating in the NCDB are the source of the de-identified data used herein;
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br level of the GFP tagged POI with vemurafenib treatment
2020-07-28
level of the GFP-tagged POI), with vemurafenib treatment compared to the DMSO-treated control (Figure 7C). This indi-cates that MEK1DD overexpression contributes to cell survival. Similarly, all nine examined kinases showed an enrichment of cell abundance in the fourth bin; in six cases, this enri
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Geneticin, G-418 Sulfate br lentivirus transduced groups As
2020-07-28
lentivirus transduced groups. As caspase 3/7 are the downstream cas-pases in the apoptosis pathway, those findings suggested that RKO or HCT 116 Geneticin, G-418 Sulfate underwent increased apoptosis after transduction of shSNRPA1 lentivirus. Therefore, SNRPA1 knocking down can promote the apoptos
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br mol This happens due to
2020-07-27
mol −1. This happens due to 7ESTAC01's ability to form an H-bond with the NH donor from the SPDP base (DA18), at a distance of 2.836 Å (Fig. 5B). After DFT calculations from ctDNA and 7ESTAC01 (free and binding), Gibbs free energy (ΔG) from the complex was low, suggesting a high affinity, showin
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br Fig Amplifications of FGFR
2020-07-26
37 Fig. 1 Amplifications of FGFR1 (Cases 30, 8, and 9) (A-H), ZNF703 (Case 18) (I), and MYC (Cases 19 and 53) (J-L) (orange, gene-specific signals; green, signals for the centromeric regions on which the specific genes are located). In Panel D, paired signals of FGFR1 and centromere 8 (small arro
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br N br O br legend on
2020-07-26
N O (legend on next page) the role of SPOP in mediating the stemness and pluripotency of PCa stem Actinomycin D and ESCs remains largely unknown. In this study, we report that SPOP inhibits the self-renewal and stem-like characteristics of PCa via the ubiquitin-depen-dent degradation o
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Segata N Izard J Waldron L Gevers
2020-07-25
[35] Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, et al. Metagenomic biomarker discovery and explanation. Genome Biol 2011;12:R60. [36] Friedman J, Alm EJ. Inferring correlation networks from genomic survey data. PLoS Comput Biol 2012;8:e1002687. [37] Ling Z, Liu X, Luo Y, Yua
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Atmospheric Environment br monitoring while
2020-07-06
Atmospheric Environment 201 (2019) 158–165 monitoring, while the geographical location of the 11 cities covers major areas of Europe such as Iberian Peninsula, Italian Peninsula, Balkan Peninsula, central continental Europe, England and Southern Scandinavian Peninsula. In Pancevo 1 (PAN), Pati
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a Department of Respiratory Medicine The Second Hospital
2020-07-06
a Department of Respiratory Medicine, The Second Hospital, Dalian Medical University, Dalian, China b Department of Scientific Research Center, The Second Hospital, Dalian Medical University, Dalian, China c Key Laboratory for Micro/Nano Technology and System of Liaoning Province, Dalian Unive
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br To achieve a precise prediction we
2020-03-24
To achieve a precise prediction, we design an ensemble regression algorithm called semi-random regression tree-based selective ensemble method (SRRT-SEM) for the second stage. Existing work on selective ensembles is usually dedicate to the techniques of selecting good Protease Inhibitor Cocktail l
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br Conclusion br EGCG as prescribed within this protocol was
2019-11-11
Conclusion EGCG as prescribed within this protocol was superior to a tradi-tional treatment in preventing radiation esophagitis. Prophylactic EGCG application for reducing radiation-induced esophagitis was superior to therapeutic one. Further studies are warranted to determine if patients with
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E E br Genes Downregulated in Polymorphonuclear Leukocytes H
2019-11-07
20 2.90E-09 4.79E-07 Genes Downregulated in Polymorphonuclear Leukocytes 9 Hours After Infection by: 20 2.90E-09 4.79E-07 Staphylococcus Aureus vs. Anaplasma phagocytophilum Anti-PD-1 and Radiation in Colorectal Cancer Supplemental Table 2 Continued Genes in P Description Ov
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Liproxstatin-1 br Previous works attempted to reach
2019-11-06
Previous works attempted to reach the same goal [36,37], sometimes by different means. For example, [email protected] [14,38] involves a daily symptom monitoring via interactive voice response at the telephone. We argue that this could be unbearable for patients in the long-term follow-up. At the s
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These authors contributed equally to this
2019-11-05
1 These authors contributed equally to this work. issues. For example, Doxorubicin (DOX), a DNA-modifying agent, shows excellent antitumor effects against multiple cancers, including cervical cancer, ovarian cancer and lung cancer (Wu et al., 2014). But, it is related to varieties of issues inc